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摘要:
Chronic pain lasting more than 3 mo,or even several years can lead to disability.Treating chronic pain safely and effectively is a critical challenge faced by clinicians.Because administration of analgesics through oral,intravenous or intramuscular routes is not satisfactory,research toward percutaneous delivery has gained interest.The transdermal patch is one such percutaneous delivery system that can deliver drugs through the skin and capillaries at a certain rate to achieve a systemic or local therapeutic effect in the affected area.It has many advantages including ease of administration and hepatic first pass metabolism avoidance as well as controlling drug delivery,which reduces the dose frequency and side effects.If not required,then the patch can be removed from the skin immediately.The scopolamine patch was the first transdermal patch to be approved for the treatment of motion sickness by the Food and Drug Administration in 1979.From then on,the transdermal patch has been widely used to treat many diseases.To date,no guidelines or consensus are available on the use of analgesic drugs through transdermal delivery.The pain branch of the Chinese Medical Association,after meeting and discussing with experts and based on clinical evidence,developed a consensus for promoting and regulating standard use of transdermal patches containing analgesic drugs.
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篇名 Expert consensus of the Chinese Association for the Study of Pain on pain treatment with the transdermal patch
来源期刊 世界临床病例杂志 学科 医学
关键词 Transdermal drug delivery systems PAIN Transdermal patches TOPICAL Nonsteroidal anti-inflammatory drugs ANALGESICS
年,卷(期) 2021,(9) 所属期刊栏目
研究方向 页码范围 2110-2122
页数 13页 分类号 R24
字数 语种
DOI
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研究主题发展历程
节点文献
Transdermal
drug
delivery
systems
PAIN
Transdermal
patches
TOPICAL
Nonsteroidal
anti-inflammatory
drugs
ANALGESICS
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界临床病例杂志
半月刊
2307-8960
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
433
总下载数(次)
1
总被引数(次)
0
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