论文降重
免费查重
Noninvasive markers of liver steatosis and fibrosis after liver transplantation-Where do we stand?
基本信息来源于合作网站，原文需代理用户跳转至来源网站获取
摘要：
In the last two decades,advances in immunosuppressive regimens have led to fewer complications of acute rejection crisis and consequently improved shortterm graft and patient survival.In parallel with this great success,long-term posttransplantation complications have become a focus of interest of doctors engaged in transplant medicine.Metabolic syndrome(MetS)and its individual components,namely,obesity,dyslipidemia,diabetes,and hypertension,often develop in the post-transplant setting and are associated with immunosuppressive therapy.Nonalcoholic fatty liver disease(NAFLD)is closely related to MetS and its individual components and is the liver manifestation of MetS.Therefore,it is not surprising that MetS and its individual components are associated with recurrent or“de novo”NAFLD after liver transplantation(LT).Fibrosis of the graft is one of the main determinants of overall morbidity and mortality in the post-LT period.In the assessment of post-LT steatosis and fibrosis,we have biochemical markers,imaging methods and liver biopsy.Because of the significant economic burden of post-LT steatosis and fibrosis and its potential consequences,there is an unmet need for noninvasive methods that are efficient and cost-effective.Biochemical scores can overestimate fibrosis and are not a good method for fibrosis evaluation in liver transplant recipients due to frequent post-LT thrombocytopenia.Transient elastography with controlled attenuation parameter is a promising noninvasive method for steatosis and fibrosis.In this review,we will specifically focus on the evaluation of steatosis and fibrosis in the post-LT setting in the context of de novo or recurrent NAFLD.
推荐文章
内容分析
关键词云
关键词热度
相关文献总数
(/次)
(/年)
文献信息
| 篇名 | Noninvasive markers of liver steatosis and fibrosis after liver transplantation-Where do we stand? | ||
| 来源期刊 | 世界移植杂志 | 学科 | 医学 |
| 关键词 | STEATOSIS FIBROSIS Noninvasive methods Transient elastography Transplantation Nonalcoholic fatty liver disease | ||
| 年，卷（期） | 2021,（3） | 所属期刊栏目 | |
| 研究方向 | 页码范围 | 37-53 | |
| 页数 | 17页 | 分类号 | R57 |
| 字数 | 语种 | ||
| DOI | |||
五维指标
引文网络
引文网络
二级参考文献 (0)
共引文献 (0)
参考文献 (0)
节点文献
引证文献 (0)
同被引文献 (0)
二级引证文献 (0)
2021(0)
- 参考文献(0)
- 二级参考文献(0)
- 引证文献(0)
- 二级引证文献(0)
研究主题发展历程
节点文献
STEATOSIS
FIBROSIS
Noninvasive
methods
Transient
elastography
Transplantation
Nonalcoholic
fatty
liver
disease
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界移植杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2220-3230
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
邮发代号：
创刊时间：
语种：
出版文献量（篇）
41
总下载数（次）
0
总被引数（次）
0
期刊文献
相关文献
推荐文献
- 期刊分类
- 期刊（年）
- 期刊（期）
- 期刊推荐
