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摘要:
BACKGROUND Patients with vasospastic angina(VSA)sometimes experience prolonged chest symptoms.The clinical characteristics of these patients have not been clarified.AIM To investigate the clinical characteristics of prolonged VSA patients.METHODS This study included 167 patients with VSA diagnosed by spasm provocation tests(SPTs)using acetylcholine,which recorded the frequencies of positive reactions to a low dose of acetylcholine(L-ACh),total occlusion due to spasm(TOC),focal spasm,and the unavoidable use of nitroglycerin(unavoidable-NTG)during SPTs.The patients underwent a medical interview that investigated the maximum duration and frequency of chest symptoms as well as the frequencies of variant angina and other serious symptoms.The patients were divided into two groups based on the maximal duration:The short-duration group(<15 min;n=114)and the long-duration group(≥15 min;n=53).They were also divided into two groups based on the frequency of chest symptoms:The low-frequency group(<4/mo;n=88)and the high-frequency group(≥4/mo;n=79).RESULTS The long-duration group showed higher frequencies of other serious symptoms(P<0.001)and variant angina(P<0.05)as well as higher frequencies of spasm induction by L-ACh(P<0.05),TOC(P<0.05),focal spasm(P<0.01),and unavoidable-NTG(P<0.01)than the short-duration group.These parameters did not differ significantly between the low-frequency and high-frequency groups.CONCLUSION These findings suggest that patients with VSA who experience prolonged chest symptoms may have more severe characteristics of VSA.
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篇名 Clinical significance of prolonged chest pain in vasospastic angina
来源期刊 世界心脏病学杂志:英文版(电子版) 学科 医学
关键词 ACETYLCHOLINE Prolonged angina attacks Variant angina Vasospastic angina Spasm provocation test PROGNOSIS
年,卷(期) 2020,(9) 所属期刊栏目
研究方向 页码范围 450-459
页数 10页 分类号 R73
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ACETYLCHOLINE
Prolonged
angina
attacks
Variant
angina
Vasospastic
angina
Spasm
provocation
test
PROGNOSIS
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研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界心脏病学杂志:英文版(电子版)
月刊
1949-8462
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
78
总下载数(次)
1
总被引数(次)
0
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