Unspecified live kidney donation by urological patients

Frank J M F Dor; Hendrikus J A N Kimenai; Jan N M IJzermans; Karel W J Klop; Michiel G H Betjes; Robert C Minnee; Sebastiaan Ceuppens; Willem Weimar; Willij C Zuidema

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Unspecified live kidney donation by urological patients

Unspecified live kidney donation by urological patients

作者：

Frank J M F Dor Hendrikus J A N Kimenai Jan N M IJzermans Karel W J Klop Michiel G H Betjes Robert C Minnee Sebastiaan Ceuppens Willem Weimar Willij C Zuidema

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Unspecified

donor

Live

kidney

donation

Benign

kidney

disorder

Living

donors

KIDNEY

Transplantation

摘要：

BACKGROUND Individuals with benign kidney disorders undergoing nephrectomy have three possibilities:Autotransplantation,with a certain risk of complications,but without a clear benefit;discarding the kidney;or living kidney donation.AIM To investigate whether patients with benign kidney disorders and a medical indication for nephrectomy are suitable as unspecified live kidney donors.METHODS We searched all clinical data from 1994-2019 for unspecified donors and their transplant recipients(n=160).Nine of these 160 donors had pre-existing kidney disorders necessitating nephrectomy and had decided to donate their kidney anonymously after discussing the possibility of kidney donation.We studied the clinical course of these nine donating patients and their transplant recipients.RESULTS Seven of nine donating patients indicated unbearable loin pain as the main complaint,one donating patient refused ureterocutaneostomy and one had two aneurysms of the renal artery.Postoperatively,seven donating patients described absence of pain and one a significant reduction after the nephrectomy.The average 1-year creatinine level in the donating patients was 88μmol/L and after a median of 6.9 years the average creatinine level was 86.6μmol/L.In the transplant recipients,one major complication occurred which led to death and in one transplant recipient graft function failed to normalize at first but has been stable for nine years now.Currently,all transplant recipients are off dialysis.CONCLUSION Our data show that patients undergoing nephrectomy as part of treatment in selected kidney disorders can function as live kidney donors.

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篇名	Unspecified live kidney donation by urological patients
来源期刊	世界移植杂志	学科	医学
关键词	Unspecified donor Live kidney donation Benign kidney disorder Living donors KIDNEY Transplantation
年，卷（期）	2020,（8）	所属期刊栏目
研究方向		页码范围	215-222
页数	8页	分类号	R69
字数		语种
DOI