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摘要:
Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and the primary reason for blindness all over the world,which is a lesion of blood vessels,neurons,and glial cells that constitute the complete structure of the retina.Patients may have vision loss and irreversible blindness.With the increase in the number of diabetes mellitus patients and the extension of lifespan,the incidence rate gradually increases.The clinical diagnosis of diabetic retinopathy mainly relies on regular examinations of ocular fundus and subjective patient descriptions,and once diabetic retinopathy is diagnosed,it is difficult to reverse.It is necessary to find the early markers of diabetic retinopathy.In this paper,data collection,data analysis of metabolomics and its research progress in diabetic retinopathy are summarized and prospected.In recent years,metabolomics has made some progress in the discovery of biomarkers,the exploration of pathogenesis,and the evaluation of diabetic retinopathyug efficacy of diabetic retinopathy.However,there are currently few metabolomics studies on the progression of diabetes mellitus to diabetic retinopathy.The determination of diabetic retinopathy-related specific biomarkers also requires data which a large number of animal experiments and clinical trials provide.In addition,despite the rapid development of metabolomics as an emerging discipline,there are still some problems,which need to be further improved in terms of analysis technology,data acquisition and data analysis.In general,there is still a lot of work to be done to apply metabolomics to clinical work.
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篇名 Research progress on metabolomics of diabetic retinopathy
来源期刊 亚洲毒理学研究 学科 医学
关键词 Metabolomics Diabetes mellitus Diabetic retinopathy Biomarkers Research progress
年,卷(期) 2020,(3) 所属期刊栏目
研究方向 页码范围 122-126
页数 5页 分类号 R58
字数 语种
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研究主题发展历程
节点文献
Metabolomics
Diabetes
mellitus
Diabetic
retinopathy
Biomarkers
Research
progress
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研究分支
研究去脉
引文网络交叉学科
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亚洲毒理学研究
季刊
2703-1583
天津市河东区大直沽中路伯苓大厦B座906
出版文献量(篇)
31
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0
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0
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