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摘要:
Metabolomics is a newly developed discipline following genomics,transcriptomics,and proteomics.It is based on the theory of systems biology,supported by modern spectroscopy analysis technology and is analyzed by the external stimulation of organisms.By analyzing the overall changes of metabolites with low molecular weight in organism after being stimulated by the outside world,we can understand the physiological and pathological state of organism,and finally clarify the essence of biological changes of organism.In recent years,metabolomics has developed rapidly.It has been widely used in early toxicity screening of lead compounds,preclinical toxicity of drugs and toxicity evaluation of clinical drugs.The in-depth interpretation of metabolomics results is also developing.This article reviewed the progress of metabolomics technology and its application in the study of toxicity evaluation of traditional Chinese medicine.
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篇名 Metabolomics and its application in the evaluation of toxicity of traditional Chinese medicine
来源期刊 亚洲毒理学研究 学科 工学
关键词 Metabolomics TOXICITY TRADITIONAL CHINESE MEDICINE Compatibility
年,卷(期) 2020,(2) 所属期刊栏目
研究方向 页码范围 61-70
页数 10页 分类号 TP3
字数 语种
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研究主题发展历程
节点文献
Metabolomics
TOXICITY
TRADITIONAL
CHINESE
MEDICINE
Compatibility
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研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
亚洲毒理学研究
季刊
2703-1583
天津市河东区大直沽中路伯苓大厦B座906
出版文献量(篇)
31
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0
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