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摘要:
BACKGROUND Laparoscopic cholecystectomy(LC)is one of the most frequently performed surgical procedures.Cystic stump leakage is an underestimated,potentially life threatening complication that occurs in 1%-6%of the patients.With a secure cystic duct occlusion technique during LC,bile leakage becomes a preventable complication.AIM To investigate the effect of polydioxanone(PDS)loop closure of the cystic duct on bile leakage rate in LC patients.METHODS In this retrospective analysis of a prospective cohort,the effect of PDS loop closure of the cystic duct on bile leakage complication was compared to patients with conventional clip closure.Logistic regression analysis was used to develop a risk score to identify bile leakage risk.Leakage rate was assessed for categories of patients with increasing levels of bile leakage risk.RESULTS Of the 4359 patients who underwent LC,136(3%)underwent cystic duct closure by a PDS loop.Preoperatively,loop closure patients had significantly more complicated biliary disease compared to the clipped closure patients.In the loop closure cohort,zero(0%)bile leakage occurred compared to 59 of 4223(1.4%)clip closure patients.For patients at increased bile leakage risk(risk score≥1)rates were 1.6%and up to 13%(4/30)for clip closure patients with a risk score≥4.This risk increase paralleled a stepwise increase of actual bile leakage complication for clip closure patients,which was not observed for loop closure patients.CONCLUSION Cystic duct closure with a PDS loop during LC may reduce bile leakage in patients at increased risk for bile leakage.
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篇名 Bile leakage after loop closure vs clip closure of the cystic duct during laparoscopic cholecystectomy:A retrospective analysis of a prospective cohort
来源期刊 世界胃肠外科杂志:英文版(电子版) 学科 医学
关键词 Laparoscopic CHOLECYSTECTOMY CYSTIC duct OCCLUSION BILE leak Endo-loop
年,卷(期) 2020,(1) 所属期刊栏目
研究方向 页码范围 9-16
页数 8页 分类号 R57
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Laparoscopic
CHOLECYSTECTOMY
CYSTIC
duct
OCCLUSION
BILE
leak
Endo-loop
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研究来源
研究分支
研究去脉
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期刊影响力
世界胃肠外科杂志:英文版(电子版)
月刊
1948-9366
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
75
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0
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