基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
BACKGROUND Atheroembolic renal disease (AERD) is caused by occlusion of the small renal arteries from embolized cholesterol crystals arising from ulcerated atherosclerotic plaques. This usually manifests as isolated renal disease or involvement from systemic atheroembolic disease. Here we report a case of AERD that responded well to steroid therapy. CASE SUMMARY A 62-year-old woman with a history of hypertension and stage IIIa chronic kidney disease was referred for rapidly worsening renal function over a 4-mo period. She complained of swollen legs, dyspnea on exertion, and two episodes of epistaxis about a month prior to admission. She reported no history of invasive vascular procedures, use of radio contrast agents, or treatment with anticoagulants or thrombolytic agents. Urinalysis showed a few red blood cells and granular casts. Serology was positive for cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA). Non-contrast-enhanced computed tomography of the chest, abdomen, and pelvis showed diffuse atherosclerotic changes in the aortic arch. Thus, c-ANCA-associated vasculitis was suspected, and the patient was started on pulse intravenous methylprednisolone. Her renal biopsy showed evidence of AERD. She was discharged with oral prednisone, and her renal function continued to improve during the initial follow-up. CONCLUSION In cases of non-vasculitis-associated ANCA, a high degree of clinical suspicion is required to pursue the diagnosis of spontaneous AERD in patients with clinical or radiological evidence of atherosclerotic burden. Although no specific treatment is available, the potential role of statins and steroids requires exploration.
推荐文章
State of rare earth elements in the rare earth deposits of Northwest Guizhou, China
Kaolinite
Clay rocks
Rare earth deposits
Element existence state
Information extraction
Northwest Guizhou Province
Rare-earth and trace elements and hydrogen and oxygen isotopic compositions of Cretaceous kaolinitic
Rare-earth and trace elements
Oxygen/hydrogen isotopic composition
Kaolinitic sediments
Lower Benue Trough
Nigeria
与Graves'Disease发病机制相关的基因研究
格雷夫斯病
甲状腺
基因芯片
免疫系统
类固醇激素
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 A rare presentation of spontaneous atheroembolic renal disease: A case report
来源期刊 世界肾病学杂志:英文版 学科 医学
关键词 Atheroembolic renal DISEASE Antineutrophil CYTOPLASMIC ANTIBODIES associated VASCULITIS Chronic KIDNEY DISEASE Case report
年,卷(期) 2019,(3) 所属期刊栏目
研究方向 页码范围 67-74
页数 8页 分类号 R
字数 语种
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (0)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
2019(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
研究主题发展历程
节点文献
Atheroembolic
renal
DISEASE
Antineutrophil
CYTOPLASMIC
ANTIBODIES
associated
VASCULITIS
Chronic
KIDNEY
DISEASE
Case
report
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界肾病学杂志:英文版
不定期
2220-6124
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
35
总下载数(次)
0
总被引数(次)
0
论文1v1指导