基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
Resistant hypertension (RH) has a prevalence of around 12% and is associated with an increased risk of cardiovascular disease,progression to end-stage renal disease,and even mortality.In 2017,the American College of Cardiology and American Heart Association released updated guidelines that detail steps to ensure proper diagnosis of RH,including the exclusion of pseudoresistance.Lifestyle modifications,such as low salt diet and physical exercise,remain at the forefront of optimizing blood pressure control.Secondary causes of RH also need to be investigated,including screening for obstructive sleep apnea.Notably,the guidelines demonstrate a major change in medication management recommendations to include mineralocorticoid receptor antagonists.In addition to advances in medication optimization,there are several device-based therapies that have been showing efficacy in the treatment of RH.Renal denervation therapy has struggled to show efficacy for blood pressure control,but with a redesigned catheter device,it is once again being tested in clinical trials.Carotid baroreceptor activation therapy (BAT) via an implantable pulse generator has been shown to be effective in lowering blood pressure both acutely and in longterm follow up data,but there is some concern about the safety profile.Both a second-generation pulse generator and an endovascular implant are being tested in new clinical trials with hopes for improved safety profiles while maintaining therapeutic efficacy.Both renal denervation and carotid BAT need continued study before widespread clinical implementation.Central arteriovenous anastomosis has emerged as another possible therapy and is being actively explored.The ongoing pursuit of blood pressure control is a vital part of minimizing adverse patient outcomes.The future landscape appears hopeful for helping patients achieve blood pressure goals not only through the optimization of antihypertensive medications but also through device-based therapies in select individuals.
推荐文章
高血压患者血压昼夜节律变化的临床意义
动态血压监测
高血压
血压负荷
缺血性卒中危险因素及4种卒中风险评分中的性别差异
缺血性卒中
危险因素
评分
性别差异
综述
老年高血压病与高血压病合并糖尿病心率变异性和动态血压变化分析
高血压
2型糖尿病
心率变异性
动态血压
自主神经系统
高血压性左心室肥厚与动态血压的相关性研究
高血压/病因学
动态血压监测
超声技术
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 Achieving control of resistant hypertension:Not just the number of blood pressure medications
来源期刊 世界高血压杂志 学科 医学
关键词 Resistant HYPERTENSION Pseudoresistance MINERALOCORTICOID receptor antagonists Device-based HYPERTENSION treatment Renal DENERVATION Carotid BARORECEPTOR activation therapy Central ARTERIOVENOUS anastomosis
年,卷(期) 2019,(1) 所属期刊栏目
研究方向 页码范围 1-16
页数 16页 分类号 R
字数 语种
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (0)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
2019(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
研究主题发展历程
节点文献
Resistant
HYPERTENSION
Pseudoresistance
MINERALOCORTICOID
receptor
antagonists
Device-based
HYPERTENSION
treatment
Renal
DENERVATION
Carotid
BARORECEPTOR
activation
therapy
Central
ARTERIOVENOUS
anastomosis
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界高血压杂志
不定期
2220-3168
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
53
总下载数(次)
0
总被引数(次)
0
论文1v1指导