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摘要:
Chronic metabolic acidosis is a common complication seen in advanced chronic kidney disease(CKD).There is currently no consensus on its management in the Republic of Ireland.Recent trials have suggested that appropriate active management of metabolic acidosis through oral alkali therapy and modified diet can have a deterring impact on CKD progression.The potential benefits of treatment include preservation of bone health and improvement in muscle function;however,present data is limited.This review highlights the current evidence,available primarily from randomised control trials(RCTs)over the last decade,in managing the metabolic acidosis of CKD and outlines ongoing RCTs that are promising.An economic perspective is also briefly discussed to support decision-making.
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篇名 Oral alkali therapy and the management of metabolic acidosis of chronic kidney disease:A narrative literature review
来源期刊 世界肾病学杂志:英文版 学科 医学
关键词 CHRONIC metabolic ACIDOSIS CHRONIC kidney disease ORAL sodium BICARBONATE ORAL ALKALI THERAPY Health economics Serum BICARBONATE
年,卷(期) 2018,(6) 所属期刊栏目
研究方向 页码范围 117-122
页数 6页 分类号 R
字数 语种
DOI
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研究主题发展历程
节点文献
CHRONIC
metabolic
ACIDOSIS
CHRONIC
kidney
disease
ORAL
sodium
BICARBONATE
ORAL
ALKALI
THERAPY
Health
economics
Serum
BICARBONATE
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界肾病学杂志:英文版
不定期
2220-6124
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
35
总下载数(次)
0
总被引数(次)
0
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