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- 世界妇产科杂志期刊 \
Hypothyroidism during pregnancy:Controversy over screening and intervention
Hypothyroidism during pregnancy:Controversy over screening and intervention
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摘要：
Thyroid hormones are critical for foetal neurological development and maternal health.Maternal hypothyroidism during pregnancy is associated with adverse impact on health of the mother as well as the progeny.Reduced thyroid hormone levels predispose the child to develop mental retardation and cognitive delay in early life.In the mother,hypothyroidism during pregnancy is associated with spontaneous abortion,placental abruption,preterm delivery and hypertensive disorders.Therefore,screening and therapeutic intervention is justified to prevent foetal as well as maternal co-morbidities.In view of impact of such a large-scale screening and intervention program on limited healthcare resources,it is debatable if a targeted rather than universal screening program will result in comparable outcomes.In addition,there is an ongoing debate regarding best evidence-based practice for the management of isolated hypothyroxinaemia,subclinical hypothyroidism and euthyroid women with autoimmune hypothyroidism.We have carried out a review of the literature;firstly,to determine whether universal screening for asymptomatic women in early pregnancy would be cost-effective.Secondly,we have retrospectively reviewed the literature to analyse the evidence regarding the impact of therapeutic intervention in women with subclinical hypothyroidism.
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| 篇名 | Hypothyroidism during pregnancy:Controversy over screening and intervention | ||
| 来源期刊 | 世界妇产科杂志 | 学科 | 医学 |
| 关键词 | Targeted SCREENING Thyroid peroxidase antibodies Isolated hypothyroxinaemia Spontaneous abortion Overt HYPOTHYROIDISM Placental ABRUPTION Universal SCREENING HYPOTHYROIDISM DURING PREGNANCY SUBCLINICAL HYPOTHYROIDISM Autoimmune HYPOTHYROIDISM | ||
| 年，卷（期） | 2018,（1） | 所属期刊栏目 | |
| 研究方向 | 页码范围 | 1-16 | |
| 页数 | 16页 | 分类号 | R |
| 字数 | 语种 | ||
| DOI | |||
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节点文献
Targeted
SCREENING
Thyroid
peroxidase
antibodies
Isolated
hypothyroxinaemia
Spontaneous
abortion
Overt
HYPOTHYROIDISM
Placental
ABRUPTION
Universal
SCREENING
HYPOTHYROIDISM
DURING
PREGNANCY
SUBCLINICAL
HYPOTHYROIDISM
Autoimmune
HYPOTHYROIDISM
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界妇产科杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2218-6220
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
邮发代号：
创刊时间：
语种：
出版文献量（篇）
123
总下载数（次）
0
总被引数（次）
0
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