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Prognostic role of tumor budding in breast cancer
Prognostic role of tumor budding in breast cancer
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摘要：
Tumor budding,defined as a small number of cancer cells observed in pathology sections detached from the main tumor mass,is a common phenomenon in cancer.It is suggested that cells in buds are in the process of actively moving away from the primary tumor in the first step of metastasis.Tumor budding has been observed in a variety of carcinomas and is best studied in colorectal cancers where it portends poor prognosis.More recently,tumor budding was found to be of prognostic significance in other cancers including breast cancer.Tumor budding in breast cancer is associated with other adverse pathologic factors,such as larger tumor size and lymphovascular invasion,but may have additional independent prognostic value.In the future,standardization of the quantification criteria for tumor budding may further aid in its adoption as a prognostic marker.
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Tumor
BUDDING
INFILTRATION
Metastasis
BREAST
cancer
Prognosis
EPITHELIAL
to
MESENCHYMAL
transition
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研究去脉
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世界实验医学杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2220-315X
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
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出版文献量（篇）
90
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0
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0
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