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Non-ossifying fibromas:Case series,including in uncommon upper extremity sites
Non-ossifying fibromas:Case series,including in uncommon upper extremity sites
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摘要：
AIM To investigate non-ossifying fibromas(NOFs)common fibrous bone lesions in children that occur in bones of the lower extremities.METHODS We analyzed 44 cases of NOF including 47 lesions,which were referred with a working diagnosis of neoplastic lesions.Lesions were located in the upper extremities(1 proximal humerus,1 distal radius)and the lower extremities(25 distal femurs,12 proximal and 4 distal tibias,and 4 proximal fibulas).RESULTS Three cases had NOFs in multiple anatomical locations(femur and fibula in 1 case,femur and tibia in 2 cases).Overall,larger lesions>4 cm and lesion expansion at the cortex were seen in 21%and 32%of cases,respectively.Multiple lesions with bilateral symmetry in the lower extremities suggest that these NOFs were developmental bone defects.Two patients suffered from fracture and were treated without surgery,one in the radius and one in the femur.Lesions in the upper extremities(i.e.,humerus of a 4-year-old female and radius of a 9-year-old male)expanded at the cortex and lesion size increased with slow ossification.CONCLUSION NOFs in the lower extremity had fewer clinical problems,regardless of their size and expansiveness.In these two upper extremity cases,the NOFs had aggressive biological features.It seems that there is a site specific difference,especially between the upper extremity and the lower extremity.Furthermore,NOFs in the radius are predisposed to fracture because of the slender structure of the radius and the susceptibility to stress.
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Non-ossifying
FIBROMA
HUMERUS
Radius
FIBULA
Upper
EXTREMITY
研究起点
研究来源
研究分支
研究去脉
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世界骨科杂志：英文版
主办单位：
百世登出版集团有限公司
出版周期：
月刊
ISSN：
2218-5836
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
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出版文献量（篇）
404
总下载数（次）
1
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0
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