基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
AIM To evaluate the risk profile of sulfur hexafluoride in voiding urosonography(VUS)based on a large cohort of children.METHODS Since 2011 sulfur hexafluoride(SH,SonoVue?,Bracco,Italy)is the only ultrasound contrast available in the European Union and its use in children has not been approved.Within a 4-year-period,531 children with suspected or proven vesicoureteral reflux(f/m=478/53;mean age 4.9 years;1 mo-25.2 years)following parental informed consent underwent VUS with administration of 2.6±1.2 mL SH in a two-center study.A standardized telephone survey on adverse events was conducted three days later.RESULTS No acute adverse reactions were observed.The survey revealed subacute,mostly self-limited adverse events in 4.1%(22/531).The majority of observed adverse events(17/22)was not suspected to be caused by an allergic reaction:Five were related to catheter placement,three to reactivated urinary tract infections,five were associated with perineal disinfection before voiding urosonography or perineal dermatitis and four with a common cold.In five patients(0.9%)hints to a potential allergic cause were noted:Perineal urticaria was reported in three interviews and isolated,mild fever in two.These were minor self-limited adverse events with a subacute onset and no hospital admittance was necessary.Ninety-six point two percent of the parents would prefer future VUS examinations with use of SH.CONCLUSION No severe adverse events were observed and indications of self-limited minor allergic reactions related to intravesical administration of SH were reported in less than 1%.
推荐文章
超声造影对膀胱输尿管反流诊断价值的探讨
超声检查
膀胱输尿管反流
诊断
The use of in-situ cosmogenic 21Ne in studies on long-term landscape development
Cosmogenic nuclides
21Ne
Long timescale
Landscape evolution
弹药的热烤(Cook-off)实验
Cook-off
含能材料
热安全性
武器弹药
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 Off-label-use of sulfur-hexafluoride in voiding urosonography for diagnosis of vesicoureteral reflux in children:A survey on adverse events
来源期刊 世界临床儿科杂志 学科 医学
关键词 VOIDING urosonography Ultrasound contrast agent Vesicoureteral REFLUX SONOVUE ADVERSE events Sulfur HEXAFLUORIDE
年,卷(期) 2017,(1) 所属期刊栏目
研究方向 页码范围 52-59
页数 8页 分类号 R
字数 语种
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (0)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
2017(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
研究主题发展历程
节点文献
VOIDING
urosonography
Ultrasound
contrast
agent
Vesicoureteral
REFLUX
SONOVUE
ADVERSE
events
Sulfur
HEXAFLUORIDE
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界临床儿科杂志
不定期
2219-2808
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
134
总下载数(次)
0
总被引数(次)
0
论文1v1指导