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摘要:
AIM To assess the potential value of femoral head(FH) volume measurements to predict joint collapse, as compared to articular surface involvement, in posttreatment osteonecrosis(ON) in pediatric patients affected by lymphoproliferative diseases.METHODS Considering 114 young patients with lymphoproliferative diseases undergone a lower-limbs magnetic resonance imaging(MRI) examination between November 2006 and August 2012 for a suspected post-treatment ON, we finally considered a total of 13 cases(7 males, mean age 15.2 ± 4.8 years), which developed a FH ON lesions(n = 23). The MRI protocol included coronal short tau inversion recovery and T1-weighted sequences, from the hips to the ankles. During the follow-up(elapsed time: 9.2 ± 2 mo), 13/23 FH articular surface(FHS)developed articular deformity. The first MRI studies with diagnosis of ON were retrospectively analyzed, measuring FH volume(FHV), FHS, ON volume(ONV) and the articular surface involved by ON(ONS). The relative involvement of FHS, in terms of volume [relative volume(RV): ONV/FHV] and articular surface [relative surface(RS): ONS/FHS], was then calculated.RESULTS By using receiver operating characteristic curve analysis(threshold of 23% of volume involvement), RV predicted articular deformity in 13/13 FHS (sensitivity 100%, specificity 90%, accuracy 95%, positive predictive value(PPV) 93%, negative predictive value(NPV) 100%)Considering a threshold of 50% of articular involvement, RS predicted articular deformity in 10/13 femoral heads(sensitivity 77%, specificity 100%, accuracy 87%, PPV 100%, NPV 77%).CONCLUSION RV might be a more reliable parameter than RS in predicting FH deformity and could represent a potential complementary diagnostic tool in the follow-up of femoral heads ON lesions.
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篇名 Relative volume measured with magnetic resonance imaging is an articular collapse predictor in hematological pediatric patients with femoral head osteonecrosis
来源期刊 世界放射学杂志:英文版(电子版) 学科 医学
关键词 OSTEONECROSIS Volume ARTICULAR surface LYMPHOPROLIFERATIVE diseases FEMORAL head Magnetic resonance imaging
年,卷(期) 2016,(8) 所属期刊栏目
研究方向 页码范围 750-756
页数 7页 分类号 R725.5
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节点文献
OSTEONECROSIS
Volume
ARTICULAR
surface
LYMPHOPROLIFERATIVE
diseases
FEMORAL
head
Magnetic
resonance
imaging
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研究分支
研究去脉
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期刊影响力
世界放射学杂志:英文版(电子版)
月刊
1949-8470
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
785
总下载数(次)
1
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0
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