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摘要:
Kidney disease is an escalating global health problem,for which the formulation of therapeutic approaches using stem cells has received increasing research attention.The complexity of kidney anatomy and function,which includes the diversity of renal cell types,poses formidable challenges in the identification of methods to generate replacement structures.Recent work using the zebrafish has revealed their high capacity to regenerate the integral working units of the kidney,known as nephrons,following acute injury.Here,we discuss these findings and explore the ways that zebrafish can be further utilized to gain a deeper molecular appreciation of renal stem cell biology,which may uncover important clues for regenerative medicine.
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篇名 Insights into kidney stem cell development and regeneration using zebrafish
来源期刊 世界干细胞杂志:英文版(电子版) 学科 医学
关键词 KIDNEY RENAL stem cell RENAL PROGENITOR REGENERATION NEPHRON Blood filter RENAL corpuscle TUBULE
年,卷(期) 2016,(2) 所属期刊栏目
研究方向 页码范围 22-31
页数 10页 分类号 R692
字数 语种
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研究主题发展历程
节点文献
KIDNEY
RENAL
stem
cell
RENAL
PROGENITOR
REGENERATION
NEPHRON
Blood
filter
RENAL
corpuscle
TUBULE
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界干细胞杂志:英文版(电子版)
月刊
1948-0210
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
526
总下载数(次)
0
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0
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