Use of stereotactic radiosurgery in the treatment of gynecologic malignancies:

A review Long B; Eskander RN; Tewari KS

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Use of stereotactic radiosurgery in the treatment of gynecologic malignancies:

Use of stereotactic radiosurgery in the treatment of gynecologic malignancies:

作者：

A review Long B Eskander RN Tewari KS

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Stereotactic

镭外科学

Stereotactic

身体放射疗法

妇科的肿瘤学

摘要：

Recent retrospective studies have reported the use ofstereotactic radiosurgery(SRS) in the treatment of gy-necologic cancers. SRS uses real-time imaging and highdose radiation beams attached to precise robotic armsto target malignant lesions while sparing normal tissue.The purpose of this review is to examine the indicationsfor SRS in gynecologic oncology, review the currentliterature regarding the use of SRS in gynecologic can-cers, and identify future directions for research in thisarea. Literature on stereotactic radiosurgery was re-viewed using the PubMed search engine. Articles writ-ten in English from 1993-2013 were reviewed, and 20 case series and clinical trials were included. The safetyand efficacy SRS has been demonstrated in all gyne-cologic disease sites including cervical, endometrial,vulvar, vaginal, and ovarian cancers. Indications for itsuse include non-central pelvic recurrences in previouslyirradiated patients, complex or non-resectable diseaserecurrence, and solitary brain metastases. Toxicitiesare usually mild, though grade 3-4 toxicities have been reported. SRS is a promising second line treatment modality for patients with primary or recurrent disease who cannot undergo standard surgical or radiation therapy. Further research is required to determine optimal dosing and fractionation schedules, delineate appropriate patient populations, and assess longterm morbidity and survival.

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篇名	Use of stereotactic radiosurgery in the treatment of gynecologic malignancies:
来源期刊	世界放射学杂志：英文版（电子版）	学科	医学
关键词	Stereotactic 镭外科学 Stereotactic 身体放射疗法妇科的肿瘤学
年，卷（期）	2014,（6）	所属期刊栏目
研究方向		页码范围	366-373
页数	8页	分类号	R
字数		语种
DOI