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摘要:
AIM:To review the relevant literature in an effort to examine the body of evidence available to date.METHODS:Ovid MEDLINE search database was queried using MeSH terms“penile induration”,“peyronie’s disease”,“Collagenases”and“Collagenase”using various permutations.No temporal parameters were employed.RESULTS:In all,5 relevant clinical trials were isolated from 34 results.These trials were analyzed using the Oxford Centre for Evidence-Based Medicine criteria.They were further examined based on study design and methods;the primary and secondary outcomes were reviewed for treatment efficacy and collagenase-related side effects.CONCLUSION:Intralesional collagenase appears to be safe and effective in the non-surgical treatment of Peyronie’s disease.However,the data remains limited and further inquiries into the safety of collagenase,treatment standardization and standardized outcomes reporting remain necessary.Furthermore,studies comparing intralesional collagenase to alternative medical and surgical therapy will be important in guiding the future treatment decision process.
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Peyronie病的临床诊治研究
Peyronie病
阴茎畸形
流行病学
阴茎白膜
内容分析
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文献信息
篇名 Use of intralesional collagenase in the treatment of peyronie’s disease:A review
来源期刊 世界临床泌尿杂志 学科 医学
关键词 Peyronie’s DISEASE COLLAGENASE RECONSTRUCTIVE UROLOGY PLAQUE INTRALESIONAL injection
年,卷(期) 2014,(3) 所属期刊栏目
研究方向 页码范围 364-369
页数 6页 分类号 R-5
字数 语种
DOI
五维指标
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研究主题发展历程
节点文献
Peyronie’s
DISEASE
COLLAGENASE
RECONSTRUCTIVE
UROLOGY
PLAQUE
INTRALESIONAL
injection
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界临床泌尿杂志
不定期
2219-2816
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
96
总下载数(次)
0
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0
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