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Varicocele and infertility:Role of pressure flow dynamics
Varicocele and infertility:Role of pressure flow dynamics
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摘要：
Varicocele is prevalent in infertile individuals as well as in normal adolescents and adults.It has an increasing trend with growing age.Infertile individuals with varicocele,develop varying degrees of sperm abnormalities that range from mild to severe semen abnormalities,even azoospermia may develop.The main proposed features of these abnormalities are incompetence of one-way valves of the draining veins of testes,that allow backflow of blood into testes.This backflow produces abnormally high intra-testicular pressure and temperature,that has been confirmed by thermography and pressure estimation in various studies.Microsurgical varicocelectomy may reverse the pathologic effects on spermatogenesis in most patients,which points towards the cause and effect relationship of varicocele with testicular damage.We propose that the prolonged effect of gravity might or may not be the initiating factor for varicocele,as in our experience,around 1/4th of hypogonadotropic hypogonadism patients who had no varicocele before treatment,developed varicocele within 3 to 6 mo of treatment with gonadotropins.Occasionally varicocele is produced by“Nutcracker phenomenon”,which is compression of left renal vein between the abdominal aorta and superior mesenteric artery.The deleterious effects of varicocele may develop slowly,causing delayed secondary infertility or rapidly,leading to azoospermia or individual may be spared of damage due to unknown factors that need further research.
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VARICOCELE
SCROTAL
Doppler
ultrasonography
Testicular
blood
FLOW
PRESSURE
FLOW
dynamics
Testes
INFERTILITY
OLIGOSPERMIA
Aesthenospermia
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研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界临床泌尿杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2219-2816
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
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出版文献量（篇）
96
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0
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0
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