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- 世界临床泌尿杂志期刊 \
Metabolic syndrome in the development and progression of prostate cancer
Metabolic syndrome in the development and progression of prostate cancer
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摘要：
Prostate cancer(PCa)is the most common noncutaneous malignancy and second leading cause of cancerspecific mortality for men in the United States.There is a wide spectrum of aggressiveness ranging from biologically significant to indolent disease,which has led to an interest in the identification of risk factors for its development and progression.Emerging evidence has suggested an association between metabolic syndrome(MetS)and PCa.MetS represents a cluster of metabolic derangements that confer an increased risk of cardiovascular disease and type 2 diabetes mellitus.Its individual components include obesity,dyslipidemias,high blood pressure,and high fasting glucose levels.MetS has become pervasive and is currently associated with a high socioeconomic cost in both industrialized and developing countries throughout the world.The relationship between MetS and PCa is complex and yet to be fully defined.A better understanding of this relationship will facilitate the development of novel therapeutic targets for the prevention of PCa and improvement of outcomes among diagnosed men in the future.In this review,we evaluate the current evidence on the role of MetS in the development and progression of PCa.We also discuss the clinical implications on the management of PCa and consider the future direction of this subject.
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| 篇名 | Metabolic syndrome in the development and progression of prostate cancer | ||
| 来源期刊 | 世界临床泌尿杂志 | 学科 | 医学 |
| 关键词 | Diabetes MELLITUS DYSLIPIDEMIAS Humans HYPERGLYCEMIA Hypertension Insulin resistance Male Metabolic syndrome X Obesity PROSTATIC neoplasms | ||
| 年，卷（期） | 2014,（3） | 所属期刊栏目 | |
| 研究方向 | 页码范围 | 168-183 | |
| 页数 | 16页 | 分类号 | R |
| 字数 | 语种 | ||
| DOI | |||
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Diabetes
MELLITUS
DYSLIPIDEMIAS
Humans
HYPERGLYCEMIA
Hypertension
Insulin
resistance
Male
Metabolic
syndrome
X
Obesity
PROSTATIC
neoplasms
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世界临床泌尿杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2219-2816
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
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96
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0
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0
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