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- 世界临床泌尿杂志期刊 \
Alternative mechanisms for prostate-specific antigen elevation:A prospective analysis of 222 transurethral resections of prostate patients
Alternative mechanisms for prostate-specific antigen elevation:A prospective analysis of 222 transurethral resections of prostate patients
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摘要：
AIM:To investigate the relationship between prostatespecific antigen(PSA)levels and(1)bladder outlet obstruction(BOO)and(2)the severity of prostate inflammation.METHODS:Two hundred and twenty-two consecutive patients undergoing transurethral resection of the prostate(TURP)were prospectively included.Patients with proven urinary tract infection and/or known prostate cancer were excluded.PSA levels,International Prostate Symptoms Score(IPSS),prostate weight,post residual volume and pressure flow parameters were determined.A histopathological assessment of the presence and severity of inflammation was also performed.RESULTS:Patients had a mean age of 69.1±8.6 years(45-90 years),with mean preoperative PSA levels of 4.7±5.4 ng/mL(0.2-32.5 ng/mL)and IPSS of 15.7±6.9(0-32).Mean PdetQmax was 96.3±34.4 cmH2O(10-220 cmH2O).The mean resected prostate weight was 39.4±27.3 g(3-189 g).Correlations were observed between PSA(logarithmic)and resected prostate weight(r=0.54;P<0.001),PSA(logarithmic)and PdetQmax(r=0.17;P=0.032),and resected prostate weight and PdetQmax(r=0.39;P<0.001).Furthermore,low correlations were observed between PSA(logarithmic)and active(r=0.21;P<0.0001)and chronic(r=0.19;P=0.005)inflammation.CONCLUSION:In this study we showed a correlation between BOO(PdetQmax)and PSA(logarithmic).Furthermore,we demonstrated a weak correlation between PSA(logarithmic)and active as well as chronic prostatic inflammation.
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| 篇名 | Alternative mechanisms for prostate-specific antigen elevation:A prospective analysis of 222 transurethral resections of prostate patients | ||
| 来源期刊 | 世界临床泌尿杂志 | 学科 | 医学 |
| 关键词 | TRANSURETHRAL resection of the PROSTATE Prostate-specific antigen BLADDER outlet OBSTRUCTION Lower URINARY TRACT symptoms PROSTATE inflammation | ||
| 年，卷（期） | 2014,（2） | 所属期刊栏目 | |
| 研究方向 | 页码范围 | 144-151 | |
| 页数 | 8页 | 分类号 | R |
| 字数 | 语种 | ||
| DOI | |||
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TRANSURETHRAL
resection
of
the
PROSTATE
Prostate-specific
antigen
BLADDER
outlet
OBSTRUCTION
Lower
URINARY
TRACT
symptoms
PROSTATE
inflammation
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研究分支
研究去脉
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世界临床泌尿杂志
主办单位：
百世登出版集团有限公司
出版周期：
不定期
ISSN：
2219-2816
CN：
开本：
出版地：
北京市朝阳区东四环中路62号楼远洋国际中
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96
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0
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0
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