Current oncologic applications of radiofrequency ablation therapies

Dhruvil R Shah; Sari Green; Angelina Elliot; John P McGahan; Vijay P Khatri

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Current oncologic applications of radiofrequency ablation therapies

Current oncologic applications of radiofrequency ablation therapies

作者：

Dhruvil R Shah Sari Green Angelina Elliot John P McGahan Vijay P Khatri

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RADIOFREQUENCY

ablation

Hepatocellular

CARCINOMA

COLORECTAL

CANCER

liver

metastasis

Lung

CANCER

Renal

cell

CARCINOMA

摘要：

Radiofrequency ablation (RFA) uses high frequency alternating current to heat a volume of tissue around a needle electrode to induce focal coagulative necrosis with minimal injury to surrounding tissues. RFA can be performed via an open, laparoscopic, or image guided percutaneous approach and be performed under general or local anesthesia. Advances in delivery mechanisms, electrode designs, and higher power generators have increased the maximum volume that can be ablated, while maximizing oncological outcomes. In general, RFA is used to control local tumor growth, prevent recurrence, palliate symptoms, and improve survival in a subset of patients that are not candidates for surgical resection. It’s equivalence to surgical resection has yet to be proven in large randomized control trials. Currently, the use of RFA has been well described as a primary or adjuvant treatment modality of limited but unresectable hepatocellular carcinoma, liver metastasis, especially colorectal cancer metastases, primary lung tumors, renal cell carcinoma, boney metastasis and osteoid osteomas. The role of RFA in the primary treatment of early stage breast cancer is still evolving. This review will discuss the general features of RFA and outline its role in commonly encountered solid tumors.

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篇名	Current oncologic applications of radiofrequency ablation therapies
来源期刊	世界胃肠肿瘤学杂志：英文版（电子版）	学科	医学
关键词	RADIOFREQUENCY ablation Hepatocellular CARCINOMA COLORECTAL CANCER liver metastasis Lung CANCER Renal cell CARCINOMA
年，卷（期）	2013,（4）	所属期刊栏目
研究方向		页码范围	71-80
页数	10页	分类号	R730.5
字数		语种
DOI