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Malaria remains a major health problem in the world.It is a neglected disease because it occurs almost exclusively in poor developing countries,which offer negligible marketable and profitable opportunities.Malaria(together with Tuberculosis),is responsible for an unprecedented global health crisis with devastating effects in developing countries.The 2011 Word Malaria Report indicated that 106 countries showed endemic malaria.Malaria control depends mainly on drug treatment,which is increasingly difficult due to the spread of drug resistant parasites and requires expensive drug combinations.Part of the inability to combat this disease is attributed to an incomplete understanding of its pathogenesis and pathophysiology.Improving the knowledge of the underlying pathogenic mechanisms of malaria transmission and of the exclusive metabolic pathways of the parasites(protozoa of the genus Plasmodium),should promote efficient treatment of disease and help the identification of novel targets for potential therapeutic interventions.Moreover,the elucidation of determinants involved in the spread of malaria will provide important information for efficient planning of strategies for targeted control.
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篇名 Recent advances and perspectives on tropical diseases:Malaria
来源期刊 世界转化医学杂志 学科 医学
关键词 MALARIA Anopheline MOSQUITOES PLASMODIUM parasites
年,卷(期) 2012,(2) 所属期刊栏目
研究方向 页码范围 4-19
页数 16页 分类号 R
字数 语种
DOI
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研究主题发展历程
节点文献
MALARIA
Anopheline
MOSQUITOES
PLASMODIUM
parasites
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相关学者/机构
期刊影响力
世界转化医学杂志
其它
2220-6132
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
48
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0
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